Lithium Orotat Capsules

What is lithium orotate? Lithium is an essential trace element that is important for the nervous system. Lithium orotate contains approximately 3.89% pure lithium, which means that 100 g of lithium orotate provides approximately 3.89 mg of elemental lithium.

Benefits of lithium orotate

1. Supports mood: Lithium orotate can help regulate mood swings and promote emotional stability.
2. Neuroprotective properties: It can help protect nerve cells and support cognitive function.
3. Reduces stress and anxiety: Studies suggest that lithium has a calming effect on the nervous system.
4. Supports brain function: Lithium may improve neurotransmitter activation and synaptic plasticity.
5. Protection against age-related cognitive decline: There is evidence that lithium may promote long-term brain health.

Possible side effects
Lithium orotate is generally well tolerated. In rare cases, fatigue, mild stomach upset or thirst may occur. People with existing kidney disease or thyroid problems should consult their doctor before taking it.

Differences from pharmaceutical lithium 
While lithium carbonate or lithium citrate is used in high doses as a medication for bipolar disorder, lithium orotate contains a much lower amount of elemental lithium.
This means it offers gentle mood support without the side effects of high-dose lithium preparations.

Lithium orotate is a promising option for people who want to support their mental health naturally. Thanks to its good bioavailability and low dosage, it can help reduce stress, promote cognitive function and stabilise emotional well-being. Nevertheless, it should always be taken with caution, especially if you have existing health conditions.

Note: This product is not a substitute for a balanced diet and healthy lifestyle. If you are unsure or have an existing medical condition, it is recommended that you consult a doctor.

Studies:

1. Comparison of lithium orotate and lithium carbonate
A review study investigated the efficacy and toxicity of lithium orotate compared to lithium carbonate. It was found that lithium orotate may have higher bioavailability, which means that it could achieve similar therapeutic effects to lithium carbonate at lower doses. It may also have a better side effect profile, which could improve patient compliance. 
https://pmc.ncbi.nlm.nih.gov/articles/PMC8413749/?utm_source=chatgpt.com

2. Animal studies on efficacy and toxicity
In an animal study in mice, lithium orotate showed higher efficacy and lower toxicity compared to lithium carbonate. The results suggest that lithium orotate could be a promising alternative to conventional lithium preparations.
https://www.biorxiv.org/content/10.1101/2022.05.01.490227v1.full?utm_source=chatgpt.com

3. Clinical studies in humans
King's College London is currently conducting a study to investigate whether lithium orotate can help people with mixed depression. In this study, participants take up to 20 mg of lithium orotate daily for up to six months. The aim is to assess blood lithium levels, compliance and the participants' experiences. 
https://www.kcl.ac.uk/research/mixli?utm_source=chatgpt.com

4. Use in other conditions
Some uncontrolled studies have investigated the use of low-dose lithium orotate in the treatment of alcoholism, migraine and depression associated with bipolar disorder. Although these studies showed positive results, further research is needed to confirm the efficacy and safety of lithium orotate in these areas of application.
https://www.drugs.com/npp/lithium-orotate.html?utm_source=chatgpt.com

Although there is some evidence that lithium orotate may be an effective and potentially better tolerated alternative to conventional lithium preparations, the current body of research is limited. Further well-designed clinical trials are needed to fully evaluate the efficacy and safety of lithium orotate.